Is it mitochondria after all? The debate is on..

The two studies I have posted before; Ruud CW Vermeulen et. Al (http://www.translational-medicine.com/content/8/1/93) and N Booth et. Al (www.ijcem.com /ISSN:1940-5901/IJCEM1204005); both agrees there is decreased mitochondrial ATP synthesis. However, there is disagreement with regard to where does the problem lie. While the first one argues that the transport capacity of oxygen is limited in CFS patients, the second study apparently finds fault with oxidative phosphorylation.

Both the studies were done by independent researchers these are yet to be validated by national health research agencies. Further, more evidence and clarity is needed with regard to where the actual problem lies, and how the mitochondria, if at all, is inhibited. Further, probably mitochondrial DNA/RNA sequencing would be able to reveal the underlying genetic mutation, if any. Also, are these inherited mutations, if any, or acquired?

Sadly, the national research agencies so far have turned a blind eye on this. More dangerously, lot of time is wasted and lost on theories on virus and others!??? while patient after patient were succumbing to the highly debilitating health condition.